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Orthopaedia

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Basic Science
Septic arthritis is an infection of the joint space caused by bacteria, fungi, mycobacteria, and viruses. Septic arthritis typically involves large joints such as the knee, hip, and shoulder, though a...

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Basic Science
Osteomyelitis is an infection of the bone caused by bacteria, fungi, or mycobacteria. The infection can land in the bone via the bloodstream (hematogenous spread), contiguous spread from adjacent soft...

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Basic Science
Lyme disease results from infection of a tick-borne spirochete, Borrelia burgdorferi. It usually presents with a characteristic rash (“erythema migrans”) at the site of the tick bite. Often, symptoms...

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Bone Metabolism and Osteoporosis
The Female Athlete Triad was initially defined as the constellation of three interrelated clinical entities typically found in active young women: amenorrhea, osteoporosis, and disordered eating. The...

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Bone Metabolism and Osteoporosis
Paget's disease of the bone is a condition of dysregulated bone remodeling, characterized by rapid osteoclastic bone resorption followed by increased osteoblastic bone formation. The resulting new bon...

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Bone Metabolism and Osteoporosis
Osteoporosis (Greek for “porous bone”) is a disease of decreased bone density leading to a predisposition to fractures. Osteoporosis is extremely common, affecting more than 200 million people worldwi...

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Basic Science
Osteonecrosis is a disease process characterized by the ischemic death of subchondral bone, that is, bone under the cartilage near the joint surface, culminating in the possible collapse of the bone a...

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Tumor
Musculoskeletal tumors are a diverse group of neoplasms that arise from various tissues of the musculoskeletal system, including bone, cartilage, muscle, and connective tissue. These tumors can be ben...

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Tumor
Metastasis is the process by which cancer spreads from its primary site of origin to other places in the body. Tumor cells escape from the primary tumor and travel in the blood stream or lymphatics to...

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