The use of biologics, which are generally made from human and/or animal materials, has significantly changed the management of rheumatoid arthritis over the last decade, becoming the cornerstone treatment for many patients. Because the arsenal of biologics for rheumatoid arthritis includes numerous monoclonal antibodies with various mechanisms of action, it can be challenging to optimize treatments for individuals.
A new review of the medical literature indicates that blood concentrations of biologics can vary from patient to patient and may correlate with therapeutic response. Therefore, the use of a 'one dose fits all' approach, mainly proposed by pharmaceutical companies, needs to be reassessed.
