Data support the use of lower disease activity cut-off points for more intensive treatments such as biologics
The results of a study presented 10-Jun-2015 at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that patients with Rheumatoid Arthritis (RA) taking conventional DMARD therapy who have moderate disease activity have a similar risk of joint failure that requires surgery as those with high disease activity.
In some countries, additional treatment with a biological DMARD is based on a disease activity cut-off that excludes RA patients with moderate disease activity. These findings suggest it is not just the RA patients with high disease activity, but also those with moderate RA, who need more intensive treatment, to reduce their risk of needing joint surgery.
