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Latest Orthopaedic News & Breaking Orthopaedic News | Orthogate Professionals

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By Editor-in-Chief
Editor-in-Chief
Latest News
09 March 2015

M-MDSCs shut down arthritis in mouse model of the disease

New research published in the Journal of Leukocyte Biology suggests that immature myeloid cells that suppress T cell activity also inhibit B cell proliferation and antibody production ameliorating arthritis

Using a mouse model of rheumatoid arthritis, scientists have discovered that a form of cellular immunotherapy by intravenous administration of monocytic myeloid-derived suppressor cells, or M-MDSCs, might be an effective treatment for the disease in humans. In a report published in the March 2015 issue of the Journal of Leukocyte Biology, researchers show that M-MDSCs are capable of inhibiting T cell proliferation, as well as B cell proliferation and antibody production.

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Last Updated: 09 March 2015
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