Maintenance notice: Some features that submit or update information are temporarily disabled while we migrate the website. You can continue browsing normally. Thank you for your understanding.
A study published online in the journal Nature Medicine suggests that local clearance of senescent cells may reduce the development of post-traumatic osteoarthritis (OA).
The authors conducted a mouse study and found that senescent cells accumulated in the articular cartilage and synovium after anterior cruciate ligament transection, and selective elimination of senescent cells attenuated the development of post-traumatic OA, reduced pain, and increased cartilage development. Further, intra-articular injection of a senolytic molecule that selectively killed senescent cells validated the results in transgenic, non-transgenic, and aged mice. Learn more...
If you have orthopedic information that you would like to share with the Orthogate Community, please register/login and submit your news, event, job, article, case or workshop from the Submit Content menu under the My Account area. Learn more!
Improving orthopaedic care, education and research using Internet technologies