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Tumor Reconstruction & Limb Salvage Journal Scan

Details
By Yu Tang; Jintao Qu; Juan Wu; Song Li; Yue Zhou; Jianru Xiao
Yu Tang; Jintao Qu; Juan Wu; Song Li; Yue Zhou; Jianru Xiao
Tumor
31 August 2015

Metastatic Spinal Cord Compression from Non-Small-Cell Lung Cancer Treated with Surgery and Adjuvant Therapies: A Retrospective Analysis of Outcomes and Prognostic Factors in 116 Patients. (from JBJS)

BACKGROUND: Metastatic spinal cord compression is a disastrous consequence of non-small-cell lung cancer (NSCLC). There have been few studies of the outcomes or prognostic factors in patients with metastatic spinal cord compression from NSCLC treated with surgery and adjuvant therapies.

METHODS: From 2002 to 2013, 116 patients with metastatic spinal cord compression from NSCLC treated with surgery and adjuvant therapies were enrolled in this retrospective analysis. Kaplan-Meier methods and Cox regression analysis were used to estimate overall survival and identify prognostic factors for survival.

RESULTS: Multivariate analysis suggested that the Eastern Cooperative Oncology Group performance status (ECOG-PS), preoperative and postoperative Frankel scores, postoperative adjuvant radiation therapy, and target therapy were independent prognostic factors.

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Last Updated: 31 August 2015
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