Total study duration up to 74 weeks: screening up to 4 weeks, AID assessment phase 12 weeks, extension phase 52 weeks, post-treatment follow-up of 6 weeks. For patients not entering the extension phas...
The purpose of this study is to assess the safety, tolerability and pharmacokinetics (PK) of two dosing regimens of multiple, subcutaneous (sc) injections of ASP2408 in patients with Rheumatoid Arthri...
All patients were performed digital radiographs which one-leg and both-leg standing anteroposterior view. Medial and lateral joint space width were measured. The severity of OA knee was identified by...