Condition : Rheumatoid Arthritis Interventions : Drug: tocilizumab [RoActemra/Actemra]; Drug: tocilizumab [RoActemra/Actemra]; Drug: tocilizumab [RoActemra/Actemra]; Drug: methotrexate; Drug: DMARD Sp...

Condition : Knee Osteoarthritis Intervention : Drug: Imrecoxib Sponsor : Jiangsu HengRui Medicine Co., Ltd. Active, not recruiting - verified November 2013

This is a prospective, multicenter, single arm feasibility study of the safety and performance of the GRADION™ Hip Total Cartilage Replacement (TCR)™ in patients who require cartilage replacement.

Conditions : Osteoarthritis; Rheumatoid Arthritis Intervention : Sponsor : Arizona Pain Specialists Not yet recruiting - verified November 2013

Condition : Rheumatoid Arthritis Interventions : Drug: tocilizumab [RoActemra/Actemra]; Drug: tocilizumab [RoActemra/Actemra]; Drug: tocilizumab [RoActemra/Actemra]; Drug: methotrexate; Drug: DMARD Sp...

Conditions : Chronic Knee Pain; Osteoarthritis, Knee Intervention : Behavioral: A worksite activity-diet intervention Sponsors : Northwestern University; National Institute of Arthritis and Musculoske...

This open-label, single-arm study will evaluate the safety and efficacy of RoActemra/Actemra alone or concomitant with other antirheumatic drugs when administered as a single, weekly injection in pati...

Condition : Rheumatoid Arthritis Intervention : Biological: Umbilical cord mesenchymal stem cells Sponsor : Translational Biosciences Recruiting - verified November 2013

Condition : Normal Human Controls Intervention : Other: Control Sponsors : Université de Sherbrooke; Janssen, LP Enrolling by invitation - verified November 2013

This is a Phase 3, long-term open-label extension study to evaluate the safety, tolerability and efficacy of tofacitinib in subjects with active PsA who have previously participated in randomized stud...