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Alkaline phosphatase An enzyme produced by osteoblasts that is believed to play a role in the mineralization of bone.

 

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Whereas osteoblasts and osteocytes are responsible for the production of bone, osteoclasts break it down. Osteoclasts are large cells, derived from stem cells in the bone marrow that give rise to the monocytemacrophage cell line. Macrophages and osteoclasts, both formed by the fusion of monocyte precursors, are multinucleated.

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