About one-third of lower-limb amputees have problems with the socket connecting their residuum to a prosthetic limb. This has led to the development of osseointegrated implants, which consist of a press-fit intramedullary implant that protrudes through the skin to accommodate an abutment to which the prosthetic limb is rigidly attached.

Concerns about ascending infection and related complications with such constructs led Al Muderis et al. to conduct a multicenter prospective cohort study on the safety of osseointegrated implants, published in the June 1, 2016 JBJS. The authors found that mild infection and irritation of soft tissue were common, but that “these complications can be managed with simple measures,” such as outpatient antibiotic treatment.

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