Data from a rabbit study published online in The American Journal of Sports Medicine suggest that current practice of treating knee ligament injuries with platelet-rich plasma (PRP) may not improve healing at low doses. 

The researchers conducted a controlled, laboratory study of 80 skeletally mature New Zealand White rabbits (160 knees), in which the medial collateral ligament (MCL) was torn midbody to simulate a grade 3 tear. Compared to a saline-injected control cohort, they found that a single dose of PRP in either 0 million/uL or 0.6 million/uL concentrations was not associated with improved ligament healing. Further, a single dose of PRP at 1.2 million/uL concentration negatively affected ligament strength and histological characteristics at 6-week follow-up. Learn more...

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