Previous study demonstrated that the condition of central cholinergic nerve is important for the postoperative cognitive dysfunction. In present study investigators hypothesized that the acetylcholine concentration in the cerebral spinal fluid is associated to the postoperative cognitive changes in aged patients undergoing osteopathic surgery.

Read more: http://www.clinicaltrials.gov/ct2/show/NCT02063542?cond=%22Arthritis%22&lup_s=01/29/2014&lup_d=30